Senior Bioinformatics Scientist

Invivoscribe is an industry pioneer, dedicated to Improving Lives with Precision Diagnostics®. Invivoscribe has been the global leader in driving international standardization of testing and accelerating patient access to the newest and best cancer treatments for over 30 years. Headquartered in sunny San Diego, California with locations across the world, we offer a comprehensive portfolio of products and services. We work with key collaborators to develop molecular assays, reagents, controls and bioinformatics tools under ISO 13485 design control that are used by over 700 clinical laboratories in over 160 countries. Our global network of laboratories offers internationally standardized next generation molecular and flow cytometry panels to support drug development and accelerate drug approvals worldwide. We work with pharmaceutical partners and international regulatory agencies across the globe to develop companion diagnostics, which are necessary to gain approval of new drugs and treatments for cancer patients. Our harmonized ISO15189 accredited and CLIA/CAP clinical laboratories offer a test menu focused on biomarkers which are clinically actionable to support therapeutic decisions, measurable residual disease (MRD) testing, patient stratification, and trial enrollment, all designed to accelerate approvals of new oncology drugs and treatments. For 30 years, we have been at forefront of precision diagnostics, and we’re just getting started! We are looking to add a Senior Bioinformatics Scientist. The Senior Bioinformatics Scientist is a hands-on technical leader with advanced knowledge of scientific principles and concepts who designs, builds, and validates production-grade bioinformatics software and scalable NGS pipelines (on-prem and cloud) to diagnose and track disease (MRD) for clinical and research applications. This role independently identifies opportunities, defines technical roadmaps, and leads delivery from requirements and design through implementation, verification/validation, release, and lifecyclesupport. Core Responsibilities Include:

• Lead the design and development of bioinformatics software and pipelines to support Whole Genome Sequencing (WGS), hybrid-capture, and amplicon based NGS assays.
• Work in close collaboration with the R&D and clinical lab teams, representing bioinformatics from a technical leadership role.
• Evaluate and develop novel methods and external tools; perform benchmarking and method comparisons, and document recommendations and decisions; own projects end-to-end.
• Develop reproducible, testable bioinformatics software using modern engineering practices (git, code review, unit/integration tests, CI/CD, containerization), and workflow technologies (e.g., Nextflow).
• Apply deep Next Generation Sequencing (NGS) analytics expertise and partner with scientific stakeholders to translate bioinformatics outputs into actionable conclusions.
• Lead bioinformatics software development for CAP/CLIA/NYA environments, including requirements definition, design documentation, verification and validation planning/execution, traceability, change control, and release documentation.
• Provide technical leadership across cross-functional teams and influence others to raise team standards (R&D, clinical labs, QA/RA, DevOps).

You Bring:

• Ph.D. degree in bioinformatics, computational biology, molecular biology, or related field with, typically, 8+ years applicable post-graduate experience. M.S. degree in bioinformatics or related field and 10+ years of applicable post-graduate experience. Equivalent combination of education and experience may be considered.
• Advanced proficiency with Linux and strong programming skills (Python, bash required; additional languages welcome).
• Experience building and/or leveraging AI agents and LLMs for various tasks and optimization of software development.
• Demonstrated experience designing and building production bioinformatics pipelines for WGS/WTS assays.
• Hands-on experience developing and operating bioinformatics software in the cloud, including workflow execution at scale and management of compute/storage costs.
• Experience collaborating across multi-disciplinary teams and providing technical leadership through influence (with or without direct reports).
• Strong foundation in statistics and quantitative analysis of biological datasets.
• Extensive background in immunology or cancer research is highly preferred.
• Experience developing software in a regulated environment is a plus (e.g. IVD, IVDR, CAP/CLIA/NYS).
• Proficient computer skills and good working knowledge of Microsoft Office programs and collaboration tools (Word, Outlook, Teams, Excel and PowerPoint) and the ability to learn new software programs.

We Bring:

• A positive workplace culture with an emphasis on support, respect and belonging.
• A diverse and inclusive work environment where you will learn, grow, and make new friends.
• Competitive pay, discretionary bonus program, incentive stock options, generous benefit options, 401k with a fully vested employer match, and generous time off benefits.

Invivoscribe is an Equal Opportunity Employer. Pay: $140,000.00 - $170,000.00 per year Work Location: Remote Apply tot his job Apply To this Job